There are two types of geothermal resources (conductive geothermal resource and convective geothermal resource) and five geothermal areas in Sichuan. Hydrogeochemical and isotope characteristics of samples from these five areas indicate that most of the geothermal fluids in Sichuan are supplied by atmospheric precipitation and the hydrogeochemical and isotope characteristics are related to the types and openness of the geothermal reservoir. The conductive geothermal resources are mainly stratified reservoir with carbonatite, while the convective geothermal resources are mainly fissure zoned reservoir and zoned and stratified combining reservoir on metamorphic rocks. The reservoir of conductive geothermal resource is more closed than the reservoir of convective geothermal resource, and the total dissolved solids as well as the therapeutic elements contents are higher than those in geothermal fluid of convective geothermal resource. For the geothermal fluid of conductive geothermal resource, it’s also more easily to form brine and has longer runoff time than the geothermal fluid of convective geothermal. This work may provide some references to the development and utilization of geothermal resources in Sichuan.