Qingjianghu geothermal water of Jiange County is belongs to the closed reduction conditions of the deep karst water in the Permian Leikou slope group gray matter dolomite and Jialingjiang group gray matter dolomite & limestone. The upper and lower layers are the thick mudstone of the Triassic Xujiahe Formation and the Tongjiezi Formation, and the shale has a good cap rock condition with respect to the aquifer and the thermal reservoir. In the northwest side of the recharge area to accept the precipitation of atmospheric precipitation, after the marine sedimentary rock salt strata, in the long distance, deep cycle of the process of strong water–rock interaction, precipitation of a large number of useful components in the rock. At the same time, under the effect of normal temperature gradient, the groundwater is gradually heated downwards to form hot mineral water containing meta-boric acid, metasilicic acid, strontium, fluorine and hydrogen sulfide. This study has important theoretical and practical significance for development of geothermal resources of the same type.